NFL Week 7 wraps up tonight with the San Francisco 49ers vs Minnesota Vikings matchup on Monday Night Football. Before MNF kicks off, let's dive into top NFL Underdog Fantasy picks for the 49ers vs Vikings game. Our top NFL picks today include 49ers WR Brandon Aiyuk and Vikings safety Camryn Bynum. As always, keep an eye on the latest NFL injury updates for MNF as Christian McCaffrey remains questionable for the game. Enjoy these NFL Underdog top plays and Monday Night Football picks as you watch tonight's game. If you're making more NFL picks tonight or setting NFL DFS lineups, check out our NFL daily projections. Now, let's dive into the top NFL Week 7 MNF picks on Underdog Fantasy for tonight's games.

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NFL Underdog Fantasy Top Picks

Week 7 Monday Night Football 49ers vs Vikings Predictions

Brandon Aiyuk, San Francisco 49ers – HIGHER Than 74.5 Receiving Yards

The San Francisco 49ers come in with a few notable injuries on offense and it should lead to Brandon Aiyuk being a top option. Deebo Samuel is out tonight with a shoulder injury and Christian McCaffrey is questionable to play with an oblique injury. It appears CMC will play, but his snaps and usage could easily be limited. If at least Samuel is out and CMC is limited and/or sidelined, then it leaves Aiyuk and George Kittle as the main receiving targets for Brock Purdy on 49ers passing plays. 

Aiyuk has 75+ receiving yards in three of five games this season with 148 and 129 in two of those. He leads the 49ers in targets, receptions, and receiving yards so far this season while averaging 90.8 ypg. With Samuel out, Aiyuk should be locked into a decent floor of receptions and yards tonight – and he’s been plenty involved even with Samuel healthy. In the four games that Samuel missed last year, Aiyuk had 80+ receiving yards in three of those four contests. We have a proven record of his yards and receiving production elevating with his teammate out. 

The Minnesota Vikings’ pass defense is about league-average this season, allowing 218.8 passing yards per game (16th in NFL). In their six games, though, four opposing WRs have gone for 70+ receiving yards. It’s not the best matchup, but Samuel's absence should force more targets Aiyuk’s way tonight. Plus, if McCaffrey is limited or out, then the 49ers could lean on the pass a bit more. Outside of Travis Kelce, opposing tight ends haven’t had much success against Minnesota this season. So if Kittle isn’t as productive, then Aiyuk could end up being Purdy’s top target here. 

Camryn Bynum, Minnesota Vikings – HIGHER Than 4.5 Solo Tackles 

We’ve had success with these defensive player stats on Underdog all season, so let’s try to pinpoint another. Camryn Bynum leads the Minnesota Vikings in solo tackles (41) and total tackles (60) this year. He also has at least five solo tackles in every game so far, averaging 6.8 solo tackles per contest. The Vikings safety is asked to make plays all over the field for this defense and that shouldn’t change tonight. 

The San Francisco 49ers offense tends to allow opposing safeties and defensive backs to be among the top tacklers. It’s a balanced offense that leans on the run more than other teams and when they do pass, we see quicker and shorter completions from Brock Purdy. Plus, without Deebo Samuel tonight, 49ers tight end George Kittle should see more targets than normal. Bynum would be covering the tight end in some man-to-man situations, raising his tackle opportunities. 

Over the 49ers' past four games, at least one opposing defensive back has had 5+ solo tackles in each game. Both of the Browns’ safeties had 5+ solo tackles last week. Against Dallas two weeks ago, one safety and one corner had 5+ solo. It sets up well for Bynum to be among the Vikings’ leading tacklers tonight and the solo track record has been there for him this year. 


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